SORBENT FOR EXTRACTION OF ANTIBODIES RAISED TO INSULIN FROM BIOLOGICAL FLUIDS AND A METHOD OF ITS PREPARING Russian patent published in 1997 - IPC

FIELD: medicine, endocrinology. SUBSTANCE: sorbent is the granulated activated carbon that has additionally insulin at amount 0.7-2.2 wt.-% bound covalently with carbon matrix functional groups. Method of sorbent making involves treatment of activated carbon with water-soluble carbodiimide and insulin solutions. Carbon matrix has static exchange volume 0.8-1.6 meq/g, pore volume is 0.5-2.0 cm³/g and specific surface - 400-1800 m²/g. Sorbent is used for extracorporal blood clearing in patients with diabetes mellitus. EFFECT: enhanced effectiveness of sorbent proposed. 2 cl, 3 tbl