PROCESS FOR PREPARING BIS(HYDROXYMETHYL)CYCLOBUTYL PURINES OR PYRIMIDINES Russian patent published in 1995 - IPC

FIELD: chemical industry. SUBSTANCE: the process for preparing bis(hydroxymethyl)cyclobutyl purines or pyridines of the formula: wherein R₁ is guanine, purine, pyrimidine- 2,6-dione, 5-methylpyrimidine-2,6-dione or 6- aminopyrimidin-2-one. Reagent 1: 1-alpha, 2-beta, 3- beta[3-(arylcyclophonyloxy-1,2-cyclobutane dimethanol), dibenzoate ester. Reagent 2: R₁-H. R₁ is defined above, this compound is optionally protected and the product resulting from condensation is deblocked. EFFECT: more efficient preparation process. 1 tbl