METHOD OF DIAGNOSIS OF NECROSIS IN HISTOLOGICAL SLICES Russian patent published in 1997 - IPC

FIELD: medicine, immunology, pathological anatomy. SUBSTANCE: method involves staining necrosis foci in histological slices followed by selective detection of pregnancy-associated α₂-glycoprotein accumulating in necrosis focus tissue. Detection of this protein involves immunohistochemical method using primary antibodies raised to α₂-glycoprotein at concentration 8-10 mcg/ml. EFFECT: increased precision of necrosis detection.