IMIDAZOLE-CONTAINING INHIBITORS OF CATHEPSIN G-INDUCED PLATELET AGGREGATION Russian patent published in 1997 - IPC

Abstract RU 2097033 C1

FIELD: medicine, pharmacology. SUBSTANCE: invention relates to imidazole-containing compounds of the general formula: , namely - histidine methyl ester dihydrochloride and lauroylhistamine that inhibit cathepsin G-induced aggregation of platelets. The proposed inhibitors can be used as reagents for homeostasis control and as pharmacological agents for thromb formation prevention, especially, at infectious and inflammatory illnesses. EFFECT: enhanced effectiveness of inhibitors. 1 tbl

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RU 2 097 033 C1

Authors

Evstigneeva R.P.

Kubatiev A.A.

Rozhkova E.A.

Zheltukhina G.A.

Tkachenko S.B.

Dates

1997-11-27Published

1994-09-30Filed