FIELD: medicine, pharmacology. SUBSTANCE: invention relates to imidazole-containing compounds of the general formula: , namely - histidine methyl ester dihydrochloride and lauroylhistamine that inhibit cathepsin G-induced aggregation of platelets. The proposed inhibitors can be used as reagents for homeostasis control and as pharmacological agents for thromb formation prevention, especially, at infectious and inflammatory illnesses. EFFECT: enhanced effectiveness of inhibitors. 1 tbl
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Authors
Dates
1997-11-27—Published
1994-09-30—Filed