PHARMACOLOGICAL AGENT "PHOTOHEME" FOR PHOTODYNAMIC CANCER THERAPY Russian patent published in 1999 - IPC

Abstract RU 2128993 C1

FIELD: medicine, oncology, pharmacology. SUBSTANCE: invention proposes lyophilizate that has, wt.-%: derivative of hematoporphyrin 76-78; sodium chloride 18-20, and water - the rest up to 100%. Hematoporphyrin derivative is prepared by successive treatment of hemin with 50% solution of hydrogen bromide in acetic acid, sodium acetate and 0.05-0.1 N solution of sodium hydroxide followed by product precipitation with acetic acid, its treatment with lower (C1-C3)-alcohol and drying. Obtained pharmacological agent is used in oncology. EFFECT: broadened pattern of highly effective anticancer preparations. 2 cl, 1 dwg, 1 ex

Similar patents RU2128993C1

Title Year Author Number
METHOD FOR PREPARING HEMATOPORPHYRIN DERIVATIVE 2002
  • Mironov A.F.
  • Ljubeshkin A.V.
RU2223963C1
METHOD OF OBTAINING DIETHRYE SALT 2,4-DI(1-METOXYETHYL)DEUTEROPORPHYRIN-IX (DIMEGIN) 2017
  • Dadeko Antonina Vladimirovna
  • Kirillova Galina Vladimirovna
  • Kojfman Oskar Iosifovich
  • Muraveva Tatyana Dmitrievna
  • Ponomarev Gelij Vasilevich
  • Trukhin Viktor Pavlovich
  • Krasilnikov Igor Viktorovich
RU2647588C1
METHOD OF INVESTIGATION OF TISSUE MALIGNIZATION IN EXPERIMENTAL ANIMALS 1993
  • Sukhin G.M.
  • Chissov V.I.
  • Rumjantseva V.D.
  • Mironov A.F.
  • Pecherskikh E.V.
  • Menenkov V.D.
RU2074718C1
METHOD OF BACTERIOCHLOROPHYLL A PREPARING 1996
  • Mironov A.F.
  • Efremov A.V.
RU2144085C1
KINETIC METHOD FOR DETECTING RHODIUM 1994
  • Fedorina L.I.
  • Levinson N.A.
  • Rysev A.P.
  • Khomutova E.G.
RU2102744C1
ARYLALIPHATIC AMINOAMIDES OF BENZOIC (SUBSTITUTED BENZOIC), CYCLOHEXANE- AND 1-ADAMANTANE CARBOXYLIC ACIDS SHOWING ANTI-ARRHYTHMIC, TOPICAL ANESTHETIC AND ANALGETIC ACTIVITY 1996
  • Borisova E.Ja.
  • Arzamastsev E.V.
  • Golovkov P.V.
  • Eliseeva I.A.
  • Bel'Tjukova A.G.
  • Terekhova O.A.
  • Cherkashin M.I.
  • Tolstikov G.A.
RU2130922C1
MEANS FOR TREATING MALIGNANT TUMORS BY APPLYING PHOTODYNAMIC THERAPY METHODS 2006
  • Solov'Eva Anna Borisovna
  • Ivanov Andrej Valentinovich
  • Konopljannikov Anatolij Georgievich
  • Filinova Elena Jur'Evna
  • Glagolev Nikolaj Nikolaevich
  • Melik-Nubarov Nikolaj Sergeevich
  • Ponomarev Gelij Vasil'Evich
  • Zhientaev Timur Makhmedovich
  • Kirjukhin Jurij Ivanovich
  • Poljakov Dmitrij Konstantinovich
  • Rogovina Svetlana Zakharovna
RU2314806C1
BIOGENIC AMINE N-ACYL DERIVATIVES ARE MODULATORS OF LIPID PEROXIDE OXIDATION, AND METHOD OF PREPARATION THEREOF 1994
  • Evstigneeva R.P.
  • Zheltukhina G.A.
  • Nebol'Sin V.E.
  • Ogrel' S.A.
  • Rozhkova E.A.
RU2093520C1
METHOD FOR PRODUCING MONOCARBOXYLIC DERIVATIVES OF DEMETALLISED PETROLEUM PORPHYRINS 2021
  • Mironov Nikolaj Aleksandrovich
  • Yakubova Svetlana Gabidullinovna
  • Zakharova Lyutsiya Yarullovna
RU2783726C1
METHOD OF PREPARING SAMPLES FOR KINETIC DETERMINATION OF RHODIUM 1994
  • Fedorina L.I.
  • Levinson N.A.
  • Rysev A.P.
  • Khomutova E.G.
RU2096755C1

RU 2 128 993 C1

Authors

Mironov A.F.

Nokel' A.Ju.

Dates

1999-04-20Published

1996-03-27Filed