FIELD: medicine, oncology, pharmacology. SUBSTANCE: invention proposes lyophilizate that has, wt.-%: derivative of hematoporphyrin 76-78; sodium chloride 18-20, and water - the rest up to 100%. Hematoporphyrin derivative is prepared by successive treatment of hemin with 50% solution of hydrogen bromide in acetic acid, sodium acetate and 0.05-0.1 N solution of sodium hydroxide followed by product precipitation with acetic acid, its treatment with lower (C1-C3)-alcohol and drying. Obtained pharmacological agent is used in oncology. EFFECT: broadened pattern of highly effective anticancer preparations. 2 cl, 1 dwg, 1 ex
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Authors
Dates
1999-04-20—Published
1996-03-27—Filed