N-PHENYLALKYL-SUBSTITUTED DERIVATIVES OF α-AMINOCARBOXAMIDE, METHOD OF THEIR SYNTHESIS, PHARMACOLOGICALLY ACTIVE COMPOSITION ON THEIR BASE AND A METHOD OF DISEASE DEVELOPMENT PROPHYLAXIS Russian patent published in 1997 - IPC

Abstract RU 2097371 C1

FIELD: organic chemistry. SUBSTANCE: invention relates to derivatives of N-phenylalkyl-substituted α-aminocarboxamide of the formula (I): α where R means furyl, thienyl, pyridyl, unsubstituted or substituted phenyl; A means or -X where X is -O-, -S- or ; , n, m and p were given in invention description; and R1, R2, R3, R4 and R5 are independently hydrogen or R6-alkyl. Invention relates to pharmaceutically acceptable salts of these compounds also. Synthesized compounds show effects on central nervous system and can be used as antiepileptic, neuroprotective agents, neurodepressants, spasmolytic and/or hypnotic drugs for human and animals treatment. EFFECT: improved method of synthesis, high effectiveness. 8 cl, 2 tbl

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RU 2 097 371 C1

Authors

Filippe Dostert[Fr]

Paolo Pevarello[It]

Franko Khejdemperger[It]

Mario Varasi[It]

Al'Berto Bonsin'Ori[It]

Romeo Ronkuchchi[It]

Dates

1997-11-27Published

1992-03-19Filed