CONJUGATES OF ANTHRACYCLINE, METHOD FOR THEIR PRODUCTION AND USING Russian patent published in 1998 - IPC

Abstract RU 2107690 C1

FIELD: medicine, namely, therapy. SUBSTANCE: conjugate is compound having formula I [A-O-W-Z]a-T where A-O is residue of any anthracycline having formula A-O-H with at least one primary or secondary hydroxyl group; a is integer from 1 to 30; N is residue of formula (2) where B is C1-C6 alkylene group; , m is 0 or 1; z is spacer group; T is part of carrier. Proposed conjugates may be used as antitumor agents. EFFECT: improved quality of desired product, improved efficiency of the method. 26 cl, 2 tbl, 5 dwg

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RU 2 107 690 C1

Authors

Franchesko Andzheluchchi[It]

Daniehla Rudzheri[It]

Stefania Stefanelli[It]

Antonio Suarato[It]

Laura Bersani[It]

Dates

1998-03-27Published

1992-08-04Filed