DERIVATIVES OF METHANEANTHRACENE, METHODS OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITION SHOWING ANTIDOPAMINEERGIC ACTIVITY Russian patent published in 1997 - IPC

Abstract RU 2099328 C1

FIELD: organic chemistry. SUBSTANCE: products: derivatives of methaneanthracene of the formula (I) given in description or their physiologically acceptable salts where X and Y were taken among hydrogen, halogen and (1-6C)-alkoxy; R1 - (1-6C)-alkyl, phenyl, phenyl-(1-3C)-alkyl, 5- or 6-membered heterocyclic rings containing 1-2 heteroatoms taken among nitrogen, oxygen and sulfur, heteroaryl-(1-3C)-alkyl. Reagent 1: compound of the formula (II) given in description. Reagent 2: R1-Li where X, Y and R1 have values indicated for compounds of the formula (I). Reaction condition: in aprotonic solvent. The synthesized compounds were used in medicine. EFFECT: improved method of synthesis. 11 cl, 4 dwg

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RU 2 099 328 C1

Authors

Robert Toms Dzhekobs[Us]

Majkl Taddeus Klajmas[Us]

Sajrus Dzhon Onmakht[Us]

Mark Ornal Terpko[Us]

Dates

1997-12-20Published

1992-08-14Filed