OXAZOLIDINE ANTIBIOTICS Russian patent published in 2014 - IPC C07D413/14 C07D417/14 C07D471/04 A61K31/4709 A61K31/498 A61K31/4985 A61K31/538 A61K31/5415 A61P31/04 C07D498/04 C07D513/04 

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to compounds of formula (I), wherein R¹ represents an alkoxy group or halogen; each U and V independently represents CH or N; "----" means a bond or is absent; W represents CH or N, or if "----" is absent, then W represents CH₂ or NH, provided not all U, V and W represent N; A represents a bond or CH₂; R² represents H, or provided A means CH₂, then it also can represent OH; each m and n are independently equal to 0 or 1; D represents CH₂ or a bond; G represents a phenyl group that is single or double substituted in meta- and/or para-position(s) by substitutes specified in alkyl, C_1-3alkoxy group and halogen, or G represents one of the groups G¹ and G²: wherein each Z¹, Z² and Z³ represents CH; and X represents N or CH and Q represents O or S; it should be noted that provided each m and n are equal to 0, then A represents CH₂; or a pharmaceutically acceptable salt of such compound. Besides, the invention refers to a pharmaceutical composition for treating a bacterial infection containing an active ingredient presented by a compound of formula (I) or a pharmaceutically acceptable salt thereof, and at least one therapeutically inert additive.

EFFECT: preparing the oxazolidine compounds applicable for preparing a drug for treating and preventing the bacterial infections.

14 cl, 8 dwg, 2 tbl, 33 ex