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2 105 569

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IPC

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Application

95109269/14, 1995-06-05

(22)

Actual filing date

1995-06-05

(45)

Published

1998-02-27

(72)

Inventor

Kolomin V.G.Polstjanov A.E.Judina T.I.Pavlova T.I.Dedjaeva E.M.

(73)

Holder

Individual'Noe Chastnoe Predprijatie Firma

METHOD OF PREPARING MEDICINAL FORMULA OF ANTITUMOR ANTIBIOTIC Russian patent published in 1998 - IPC

Abstract RU 2105569 C1

FIELD: pharmacy. SUBSTANCE: method is designed for preparing medicinal formula of antitumor antibiotic ruboxyl. Method involves addition of an alkaline agent to ruboxyl an aqueous solution, filtration under vacuum and pouring in vials followed by freezing to (-50)-(-30) C and keeping at this temperature for 1-1.5 h. Drying is carried out without heating and at heating at the rate 5 C/h, not above, to 20-25 C, kept at this temperature 2-6 h, not less. Alkaline agent used: 2-% solution of NaOH added to pH 7.0-8.0 to ruboxyl solution. EFFECT: improved method of preparing. 3 cl, 1 tbl

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RU 2 105 569 C1

Authors

Kolomin V.G.

Polstjanov A.E.

Judina T.I.

Pavlova T.I.

Dedjaeva E.M.

Dates

1998-02-27—Published

1995-06-05—Filed

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