FIELD: pharmaceutics. SUBSTANCE: method resides in applying nifedipine on water-soluble carrier in mixture with polyvinyl pyrrolidone and pharmaceutically acceptable acryl polymer, polyvinyl pyrrolidone-to-nifedipine weight ratio is from 1:1 to 1:10, and acryl polymer-to-nifedipine weight ratio is from 1: 4 to 1:20. Proposed compositions are suitable for administering nifedipine once a day. EFFECT: higher efficiency. 16 cl, 5 dwg, 3 tbl
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Authors
Dates
1998-03-10—Published
1993-01-12—Filed