FIELD: medicine; pharmacology.
SUBSTANCE: minitablets have a kernel and an external cover which makes 2-15% of gross weight of minitablets, the kernel of the specified minitablets, includes a venlafaxine hydrochloride, microcrystallic cellulose and a polyvinylpyrolidone, and the specified cover includes polymer, insoluble in water, and a polymer, soluble in water.
EFFECT: provision of levels of concentration in a blood plasma above the minimum therapeutic concentration during the long period of time.
10 cl, 1 dwg, 1 tbl, 5 ex
| Title | Year | Author | Number |
|---|---|---|---|
| VENLAFAXINE HYDROCHLORIDE SUSTAINED RELEASE COMPOSITION, FILM COVER COMPOSITION, METHOD OF PROVIDING THERAPEUTICALLY ACTIVE VENLAFAXINE CONCENTRATION AND METHOD OF EXCLUDING ZERO AND PEAK CONCENTRATIONS OF MEDICINAL AGENT | 1997 |
|
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