FIELD: pharmaceutics. SUBSTANCE: composition comprises pharmacologically active compound or its pharmaceutically acceptable substituent, aqueous-alcoholic solvent containing 15-75 vol.% of ethanol, and penetration-enhancing agent constituted by 1-alkyl-transcycloheptane-2-one containing C8-16 or cis-olefin compound of formula (1) CH3(CH2)xCH = CH(CH2)yCOOH, where X and Y represent each integer from 4 to 10, and sum of X and Y is equal from 10 to 16 in the amount of 0.01-5 vol.%. EFFECT: enhanced skin-penetrating capacity. 8 cl, 11 tbl
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| TRANSDERMAL DELIVERY SYSTEM |
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1993 |
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| METHOD FOR INHIBITING REDUCTION OF TRANSDERMAL DRUG MOVEMENT BY INHIBITING PATHS CLOSING |
2001 |
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