METHOD OF PREPARING THE COMPLEX OF SILIBININE WITH CYCLODEXTRIN, INCLUSION COMPLEX OF SILIBININE WITH CYCLODEXTRIN, PHARMACEUTICAL COMPOSITION SHOWING ANTIHEPATOTOXIC ACTIVITY AND A METHOD OF ITS PREPARING Russian patent published in 1998 - IPC

Abstract RU 2108109 C1

FIELD: chemical-pharmaceutical industry. SUBSTANCE: invention relates to new complexes including silibinine with cyclodextrin and presented by groups consisting of α-,β-,γ--cyclodextrin and their corresponding derivative, and a method of their preparing. New complexes containing silibinine show enhanced biological activity as compared with silibinine and can be used in medicine for treatment of different hepatotoxic states. EFFECT: improved method of preparing, enhanced effectiveness. 5 cl

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RU 2 108 109 C1

Authors

Umberto Valkavi[It]

Vintsentso Monterosso[It]

Roberto Kaponi[It]

Ehnriko Bozone[It]

Vil'Frid Peter Vakhter[De]

Jozhef Sejtli[Hu]

Dates

1998-04-10Published

1991-03-28Filed