N-MORPHOLINO-N-NITROSOAMINOACETONITRILE AND CYCLODEXTRIN OR CYCLODEXTRIN DERIVATIVE INCLUSION COMPLEXES AND METHOD OF PREPARING THEREOF, PHARMACEUTICAL COMPOSITION, AND METHOD OF AFFECTING LIVING CELLS WITH NITROGEN OXIDE Russian patent published in 1999 - IPC

Abstract RU 2136698 C1

FIELD: chemical industry. SUBSTANCE: described are new N-morpholino-N-nitrosoaminoacetonitrile and cyclodextrin or hydroxypropylated cyclodextrin or methylated cyclodextrin inclusion complexes which comprise, as catalyst or stabilizer, ions in the form of ammonium salt or alkali metal salt of said complex. Said complexes are stable in solid state, and give off nitrogen oxide at room temperature when dissolved in water or water systems. Described are method of preparing said complexes, pharmaceutical composition based on said complexes and capable of isolating nitrogen oxide and method of affecting living cells with nitrogen oxide. Nitrogen oxide is involved in many major bioregulation processes. EFFECT: improved properties of the pharmaceutical composition. 17 cl, 2 dwg, 20 ex, 4 tbl

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RU 2 136 698 C1

Authors

Getsi Joshep

Vikmon Andrashneh

Sejtli Jozhef

Sente Lajosh

Seman Julianna

Dates

1999-09-10Published

1995-04-25Filed