COMPLEX INCLUDING N-ETHOXYCARBONYL-3- MORPHOLINESYDNONEIMINE OR SALT THEREOF WITH CYCLODEXRIN OR CYLODEXTRIN DERIVATIVE, METHOD OF PREPARING SAID INCLUSION CONTEX, PHARMACEUTICAL COMPOSITIONS AND METHOD OF PREPARATION THEREOF, AND TREATMENT METHOD Russian patent published in 1998 - IPC

Abstract RU 2111216 C1

FIELD: pharmaceutical industry. SUBSTANCE: present invention describes complexes including N-ethoxycarbonyl-3- morpolinesydnoneimine or salts thereof with cyclodextrin or derivatives thereof, preparation thereof and pharmaceutical composition which comprise said complexes. Complex including N-ethoxycarbonyl-3-morpholine- sydnoneimine is prepared by (a) reacting N- ethoxycarbonyl-3-morpholinesydnoneimine or salt thereof and cyclodextrin derivative in solvent and optionally separating complex from solution by removal of water or (b) by vigorously grinding mixture of N-ethoxycarbonyl-3- morpholinesydnoneimine or salt thereof with cyclodextrin derivative. EFFECT: more efficient preparation method. 13 cl, 3 tbl

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RU 2 111 216 C1

Authors

Marija Vikmon[Hu]

Jozhef Sejtli[Hu]

Jozhef Gaal[Hu]

Ishtvan Khermets[Hu]

Agnesh Khorvat[Hu]

Katalin Marmaroshi[Hu]

Gabor Khorvat[Hu]

Irejn Munkachi[Hu]

Dates

1998-05-20Published

1991-03-28Filed