NIMEZULIDE SALT-CYCLODEXTRIN INCLUSION COMPLEXES, METHOD OF PREPARING THEREOF AND PHARMACEUTICAL AGENT HAVING ANTIINFLAMMATORY AND ANALGESIC ACTIVITIES Russian patent published in 1999 - IPC

Abstract RU 2129564 C1

FIELD: pharmaceutical industry. SUBSTANCE: invention describes alkali and alkaline-earth metal nimezulide salt inclusion complexes of general formula I: wherein A is alkali or alkaline-earth metal with cyclodextrin or cyclodextrin alkyl-or hydroxyalkyl derivatives at molar ratio of salt to cyclodextrin or derivative thereof from 1:1 to 1:2, respectively. Pharmaceutical agent comprising, as active ingredient, compound of formula I has antiinflammatory and analgesic effects. EFFECT: improved properties of the pharmaceutical agent. 12 cl, 2 dwg, 17 ex, 3 tbl

Similar patents RU2129564C1

Title Year Author Number
N-MORPHOLINO-N-NITROSOAMINOACETONITRILE AND CYCLODEXTRIN OR CYCLODEXTRIN DERIVATIVE INCLUSION COMPLEXES AND METHOD OF PREPARING THEREOF, PHARMACEUTICAL COMPOSITION, AND METHOD OF AFFECTING LIVING CELLS WITH NITROGEN OXIDE 1995
  • Getsi Joshep
  • Vikmon Andrashneh
  • Sejtli Jozhef
  • Sente Lajosh
  • Seman Julianna
RU2136698C1
WATER-SOLUBLE NIMESULID AND L-LYSINE SALT, METHOD OF ITS PREPARING, COMPOSITION BASED ON THEREOF, NIMESULID SALT AQUEOUS SOLUTION, PHARMACEUTICAL COMPOSITION WITH ANTI-INFLAMMATORY ACTIVITY 1995
  • Pirott Bernar
  • Piel' Zheral'Din
  • Neven Filipp
  • Del'Nevij Izabel'
  • Zheszi Zhozef
RU2151764C1
METHOD OF PREPARING BENZIMIDAZOLE DERIVATIVES STABLE IN ACID MEDIUM 1992
  • Dong San Min[Kr]
  • Ki An Um[Kr]
  • Jong Soo Kim[Kr]
  • P'Eong Uk Park[Kr]
RU2105773C1
METHOD OF PREPARING THE COMPLEX OF SILIBININE WITH CYCLODEXTRIN, INCLUSION COMPLEX OF SILIBININE WITH CYCLODEXTRIN, PHARMACEUTICAL COMPOSITION SHOWING ANTIHEPATOTOXIC ACTIVITY AND A METHOD OF ITS PREPARING 1991
  • Umberto Valkavi[It]
  • Vintsentso Monterosso[It]
  • Roberto Kaponi[It]
  • Ehnriko Bozone[It]
  • Vil'Frid Peter Vakhter[De]
  • Jozhef Sejtli[Hu]
RU2108109C1
STABLE AQUEOUS COMPOSITIONS OF CYCLODEXTRIN INCLUSION COMPOUNDS, COMPOUNDS INCLUDING α-,β- or γ- DEXTRIN OR ITS ALKYL- OR HYDROXYALKYL DERIVATIVES AND (6R)-OR (6S)-5,10- METHYLENE TETRAHYDROFOLIC ACID OR ITS SALT, METHOD OF STABILIZING AQUEOUS SOLUTIONS, AND METHOD OR PREPARING STABLE SOLUTIONS 1993
  • Khans Rudol'F Mjuller
  • Martin Ul'Mann
  • Jozef Konti
RU2135519C1
PARENTERAL LIQUID PREPARATION INCLUDING CARBAMATE COMPOUND 2017
  • Baek, Myoung Ki
  • Lee, Ji Hye
  • Choi, So Young
RU2761041C2
PHARMACEUTICAL COMPOSITION FOR SUSTAINED-RELEASE OF ACTIVE SUBSTANCES (VARIANTS) AND METHOD OF ITS PREPARING (VARIANTS) 1998
  • Fehnara Domeniko
  • Bervaer Monik
  • Bukell' Ehnn
  • Delirs Mishel'
RU2179017C2
INCLUSION COMPLEX OF 3-MORPHOLINOSIDNONIMIN OR SALT THEREOF OR TAUTOMERIC ISOMER THEREOF WITH CYCLODEXTRIN OR ITS DERIVATIVE, METHOD FOR ITS PRODUCTION AND PHARMACEUTICAL COMPOSITION CONTAINING IT, METHOD FOR PRODUCING PHARMACEUTICAL COMPOSITION AND METHOD FOR TREATING STENOCARDIA AND HEART'S ISCHEMIC DISEASE IN HUMANS 1991
  • Marija Vikmon[Hu]
  • Jozhef Sejtli[Hu]
  • Lajosh Sente[Hu]
  • Jozhef Gaal[Hu]
  • Ishtvan Khermets[Hu]
  • Agnesh Khorvat[Hu]
  • Katalin Marmaroshi[Hu]
  • Gabor Khorvat[Hu]
  • Irejn Munkachi[Hu]
RU2107695C1
PHARMACEUTICAL COMPOSITION 2003
  • Ito Susei
  • Miva Akio
  • Nakano Mari
RU2313346C2
COMPLEX INCLUDING N-ETHOXYCARBONYL-3- MORPHOLINESYDNONEIMINE OR SALT THEREOF WITH CYCLODEXRIN OR CYLODEXTRIN DERIVATIVE, METHOD OF PREPARING SAID INCLUSION CONTEX, PHARMACEUTICAL COMPOSITIONS AND METHOD OF PREPARATION THEREOF, AND TREATMENT METHOD 1991
  • Marija Vikmon[Hu]
  • Jozhef Sejtli[Hu]
  • Jozhef Gaal[Hu]
  • Ishtvan Khermets[Hu]
  • Agnesh Khorvat[Hu]
  • Katalin Marmaroshi[Hu]
  • Gabor Khorvat[Hu]
  • Irejn Munkachi[Hu]
RU2111216C1

RU 2 129 564 C1

Authors

Zhozef Getsi

Dates

1999-04-27Published

1994-05-18Filed