FIELD: pharmaceutical industry. SUBSTANCE: invention describes alkali and alkaline-earth metal nimezulide salt inclusion complexes of general formula I: wherein A is alkali or alkaline-earth metal with cyclodextrin or cyclodextrin alkyl-or hydroxyalkyl derivatives at molar ratio of salt to cyclodextrin or derivative thereof from 1:1 to 1:2, respectively. Pharmaceutical agent comprising, as active ingredient, compound of formula I has antiinflammatory and analgesic effects. EFFECT: improved properties of the pharmaceutical agent. 12 cl, 2 dwg, 17 ex, 3 tbl
Title |
Year |
Author |
Number |
N-MORPHOLINO-N-NITROSOAMINOACETONITRILE AND CYCLODEXTRIN OR CYCLODEXTRIN DERIVATIVE INCLUSION COMPLEXES AND METHOD OF PREPARING THEREOF, PHARMACEUTICAL COMPOSITION, AND METHOD OF AFFECTING LIVING CELLS WITH NITROGEN OXIDE |
1995 |
- Getsi Joshep
- Vikmon Andrashneh
- Sejtli Jozhef
- Sente Lajosh
- Seman Julianna
|
RU2136698C1 |
WATER-SOLUBLE NIMESULID AND L-LYSINE SALT, METHOD OF ITS PREPARING, COMPOSITION BASED ON THEREOF, NIMESULID SALT AQUEOUS SOLUTION, PHARMACEUTICAL COMPOSITION WITH ANTI-INFLAMMATORY ACTIVITY |
1995 |
- Pirott Bernar
- Piel' Zheral'Din
- Neven Filipp
- Del'Nevij Izabel'
- Zheszi Zhozef
|
RU2151764C1 |
METHOD OF PREPARING BENZIMIDAZOLE DERIVATIVES STABLE IN ACID MEDIUM |
1992 |
- Dong San Min[Kr]
- Ki An Um[Kr]
- Jong Soo Kim[Kr]
- P'Eong Uk Park[Kr]
|
RU2105773C1 |
METHOD OF PREPARING THE COMPLEX OF SILIBININE WITH CYCLODEXTRIN, INCLUSION COMPLEX OF SILIBININE WITH CYCLODEXTRIN, PHARMACEUTICAL COMPOSITION SHOWING ANTIHEPATOTOXIC ACTIVITY AND A METHOD OF ITS PREPARING |
1991 |
- Umberto Valkavi[It]
- Vintsentso Monterosso[It]
- Roberto Kaponi[It]
- Ehnriko Bozone[It]
- Vil'Frid Peter Vakhter[De]
- Jozhef Sejtli[Hu]
|
RU2108109C1 |
STABLE AQUEOUS COMPOSITIONS OF CYCLODEXTRIN INCLUSION COMPOUNDS, COMPOUNDS INCLUDING α-,β- or γ- DEXTRIN OR ITS ALKYL- OR HYDROXYALKYL DERIVATIVES AND (6R)-OR (6S)-5,10- METHYLENE TETRAHYDROFOLIC ACID OR ITS SALT, METHOD OF STABILIZING AQUEOUS SOLUTIONS, AND METHOD OR PREPARING STABLE SOLUTIONS |
1993 |
- Khans Rudol'F Mjuller
- Martin Ul'Mann
- Jozef Konti
|
RU2135519C1 |
PARENTERAL LIQUID PREPARATION INCLUDING CARBAMATE COMPOUND |
2017 |
- Baek, Myoung Ki
- Lee, Ji Hye
- Choi, So Young
|
RU2761041C2 |
PHARMACEUTICAL COMPOSITION FOR SUSTAINED-RELEASE OF ACTIVE SUBSTANCES (VARIANTS) AND METHOD OF ITS PREPARING (VARIANTS) |
1998 |
- Fehnara Domeniko
- Bervaer Monik
- Bukell' Ehnn
- Delirs Mishel'
|
RU2179017C2 |
INCLUSION COMPLEX OF 3-MORPHOLINOSIDNONIMIN OR SALT THEREOF OR TAUTOMERIC ISOMER THEREOF WITH CYCLODEXTRIN OR ITS DERIVATIVE, METHOD FOR ITS PRODUCTION AND PHARMACEUTICAL COMPOSITION CONTAINING IT, METHOD FOR PRODUCING PHARMACEUTICAL COMPOSITION AND METHOD FOR TREATING STENOCARDIA AND HEART'S ISCHEMIC DISEASE IN HUMANS |
1991 |
- Marija Vikmon[Hu]
- Jozhef Sejtli[Hu]
- Lajosh Sente[Hu]
- Jozhef Gaal[Hu]
- Ishtvan Khermets[Hu]
- Agnesh Khorvat[Hu]
- Katalin Marmaroshi[Hu]
- Gabor Khorvat[Hu]
- Irejn Munkachi[Hu]
|
RU2107695C1 |
PHARMACEUTICAL COMPOSITION |
2003 |
- Ito Susei
- Miva Akio
- Nakano Mari
|
RU2313346C2 |
COMPLEX INCLUDING N-ETHOXYCARBONYL-3- MORPHOLINESYDNONEIMINE OR SALT THEREOF WITH CYCLODEXRIN OR CYLODEXTRIN DERIVATIVE, METHOD OF PREPARING SAID INCLUSION CONTEX, PHARMACEUTICAL COMPOSITIONS AND METHOD OF PREPARATION THEREOF, AND TREATMENT METHOD |
1991 |
- Marija Vikmon[Hu]
- Jozhef Sejtli[Hu]
- Jozhef Gaal[Hu]
- Ishtvan Khermets[Hu]
- Agnesh Khorvat[Hu]
- Katalin Marmaroshi[Hu]
- Gabor Khorvat[Hu]
- Irejn Munkachi[Hu]
|
RU2111216C1 |