FIELD: analytical biochemistry, toxicology. SUBSTANCE: method involves globin purification and preparing samples for quantitative determination. Quantitative determination of acrylonitrile is carried out by gas chromatography and mass-spectrometry method. Samples are prepared by sulfur atom oxidation in alkylated proteins to sulfoxide form using hydrogen peroxide followed by acrylonitrile release from sulfoxide form at 250 ± 5 C in injection chamber of gas chromatograph device. EFFECT: improved method of analysis. 2 dwg, 2 tbl
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Authors
Dates
1998-05-10—Published
1992-11-04—Filed