METHOD FOR EARLIER DIAGNOSTICS OF INTRAUTERINE INFECTION Russian patent published in 1998 - IPC

FIELD: medicine, obstetrics, gynecology, diagnostics. SUBSTANCE: blood sampling is conducted in women at the second trimester of their pregnancy to determine the presence of C-reactive protein by using immunological method of capillary precipitation and that of placental alpha-1-microglobulin by applying "Placental alpha-1-microglobulin-Fertitest" which is based upon the usage of monoclonal antibodies. To conduct bacteriological and cytological trials it is necessary to observe smears taken from cervical canal of uterine cervix and posterior vaginal fornix for further detection of inflammatory reaction signs caused by different specific and non-specific microflora. At the level of placental alpha-1-microglobulin > or = 30 ng/ml, at the absence of C-reactive protein and noninfected genital organs a placental deficiency of non-infectious genesis is predicted, and at the level of placental alpha-1-microglobulin > or = 30 ng/ml, at the presence of C-reactive protein and infected genital organs an intrauterine infection (placental deficiency of infectious genesis) is predicted. EFFECT: higher specificity and accuracy of diagnostics.