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2 110 990

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C1

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IPC

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Application

94027343/14, 1994-07-14

(22)

Actual filing date

1994-07-14

(45)

Published

1998-05-20

(72)

Inventor

Shanskaja A.I.Krivoruchko B.I.Bulusheva E.V.Jakovleva T.E.Puchkova S.M.Nedachina N.A.Smirnov A.V.Kashina E.A.

(73)

Holder

Rossijskij Nauchno-Issledovatel'Skij Institut Gematologii I Transfuziologii

LIPOSOMAL VESICLE WITH CYTOCHROME C Russian patent published in 1998 - IPC

Abstract RU 2110990 C1

FIELD: biotechnology. SUBSTANCE: liposomal vesicle with lipid envelope consisting of lecithin and cholesterol and can be used in medicine, in part, in pharmacology. Lipid envelope of vesicle has additionally a mixture of acid phospholipids. Indicated mixture is isolated as a united negatively charged phospholipid component from soybean phosphatides. Vesicle has additionally incapsulated cytochrome c taken at ratio to lipid envelope (mas. p. p.) = 1:(6-8). Lipid envelope of vesicle can has additionally tocopherol taken at amount 1.1-2.2% of total lipid envelope mass. EFFECT: enhanced therapeutic effectiveness and prolonged effect as compared with native form of cytochrome c. 3 tbl

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RU 2 110 990 C1

Authors

Shanskaja A.I.

Krivoruchko B.I.

Bulusheva E.V.

Jakovleva T.E.

Puchkova S.M.

Nedachina N.A.

Smirnov A.V.

Kashina E.A.

Dates

1998-05-20—Published

1994-07-14—Filed

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