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2 071 765

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C1

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IPC

(21) (22)

Application

94027344/14, 1994-07-14

(22)

Actual filing date

1994-07-14

(45)

Published

1997-01-20

(72)

Inventor

Shanskaja A.I.Bulusheva E.V.Jakovleva T.E.Nedachina N.A.

(73)

Holder

Rossijskij Nauchno-Issledovatel'Skij Institut Gematologii I Transfuziologii

METHOD OF LIPOSOME PREPARATION Russian patent published in 1997 - IPC

Abstract RU 2071765 C1

FIELD: medicine, pharmacology. SUBSTANCE: method involves lecithin and acid phospholipids mixture dissolving isolated from soy bean phosphatides as a single component in organic solvent, drying the obtained solution with film formation, lipid film resuspending in the dispersed medium and dispersion of the suspended lipids into microemulsion by passing suspension through microgap at pressure gradient 50-300 atm up to the normal value. Dispersion medium: aqueous solutions of cytostatics, immunomodulating agents, polyunsaturated fatty acids isolated from marine animals. EFFECT: enhanced quality of liposomes, decreased oxidizability. 5 tbl

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RU 2 071 765 C1

Authors

Shanskaja A.I.

Bulusheva E.V.

Jakovleva T.E.

Nedachina N.A.

Dates

1997-01-20—Published

1994-07-14—Filed

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