DERIVATIVES OF 7-(2-AMINOETHYL)-BENZOTHIAZOLONE OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS, METHODS OF THEIR SYNTHESIS, DERIVATIVES OF N-[2-(4-HYDROXY-2-OXO-3H-1,3-BENZOTHIAZOLE-7-YL]-ETHYLAMIDE, PHARMACEUTICAL COMPOSITION SHOWING AGONISTIC ACTIVITY RELATIVE TO β-ADRENORECEPTORS Russian patent published in 1998 - IPC

FIELD: organic chemistry, heterocyclic compounds. SUBSTANCE: product: derivatives of 7-(2-aminoethyl)-benzothiazolone of the formula (I) β₂ where X and Y mean independently or -O-; n = 0, 1 or 2; p, q and r mean independently 2 or 3; Z means phenyl possibly substituted with halogen, -S(O)_n- or -OR¹,NO₂ or Z means 5- or 6- membered unsaturated heterocycle containing N or S; NH₂ means hydrogen or R¹-alkyl, or their pharmaceutically acceptable salts. Invention describes methods of their synthesis and pharmaceutical compositions containing thereof and also intermediate compounds for their synthesis of the formula (Va): C₁-C₆ where p, q and r, X, Y have indicated values and Z - phenyl optionally substituted with halogen atom, or NO₂,NH₂ where OR¹ - H or R¹--alkyl. Synthesized compounds show agonistic activity relative to C₁-C₆-adrenoreceptors. EFFECT: improved method of synthesis. 11 cl, 3 tbl