METHOD OF PREPARING 7,7-DIOXIDE 5,6-DIHYDRO (S) -4- (ALKILAMINO)-(S)-6- ALKYL-4H- THIENO (2,3-b) THIOPYRAN - 2-SULFONAMIDE AND 7,7-DIOXIDE 5,6-DIHYDRO(S)-4- (ACYLAMIDO)-(S)-6-ALKYL-4H-THIENO (2,3-b)THIOPYRAN Russian patent published in 1998 - IPC

Abstract RU 2114851 C1

FIELD: pharmaceutical industry. SUBSTANCE: 7,7-dioxide 5,6-dihydro-4- (ethylamino)-6- methyl-5H- thieno (2,3-b) thiopyran sulfonamide is prepared by reacting 7,7-dioxide thieno (2,3-b) thiopyran hydroxyderivative with acetonitrile followed by addition of sulfonamide group to second position of heterocyclic system. The claimed method make it possible to carry out synthesis to retain molecule chirality. The above-mentioned compound is useful in pharmacology for regulating intra pressure. EFFECT: improved properties of the title compounds. 9 cl

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RU 2 114 851 C1

Authors

Pol Sokhar

Dehvid Dzh.Matr

Tomas Dzh.Blehklok

Dates

1998-07-10Published

1994-03-16Filed