FIELD: medicine, oncology, pharmacy. SUBSTANCE: capsules have an active substance, loosening agent and alkaline agent. Capsules have low-substituted hydroxypropylcellulose, carboxymethylstarch sodium, partially sized starch, cross-linked polyvinylpyrrolidone as a loosening agent at amount 0.5-4 wt.-% per 1 wt.-% an active component. Alkaline agent is taken at amount 0.002-0.3 mas. p. per 1 mas. p. an active component. An active component can be as a part of capsule taken at amount 5-50 wt.-% of other component mass. Capsules ensure the high stability of cytarabine ocphosphate and its good degradability in acid solutions. The proposed capsules can be used for oral administration as antileukimec agents. EFFECT: improved quality and effectiveness of capsules. 7 cl, 2 tbl
Authors
Dates
1998-07-27—Published
1993-04-02—Filed