FIELD: medicine, organic technology. SUBSTANCE: 2,3-dihydro-1,4-benzodioxine-5-yl-pyperazine derivatives have formula I wherein R1 is halogen, lower alkyl or alkoxyl, hydroxyl or cyan group, m=1 or 2, n=0 or 1. A is alkylene chain comprising 2-6 carbon atoms which may be substituted by one or two lowers alkyl groups or by one phenyl group. B is methylene, ethylene, carbonyl, sulfunyl, sulfonyl or sulfur. Proposed compounds or salts thereof posses 5-HT1A-antagonist activity. EFFECT: improved quality of product. 1 tbl
Title |
Year |
Author |
Number |
DERIVATIVES OF PIPERAZINE |
1998 |
- Fenstra Rulof Villem
- Den Khartog Jakobus Antonius Josef
- Krjuse Kornelis Gerrit
- Tjulp Martinus Teodorus Marija
- Long Stiven Kennet
|
RU2197488C2 |
DERIVATIVES OF PIPERAZINE AND PIPERIDINE AND METHOD OF THEIR SYNTHESIS |
1997 |
- Fenstra Rulof Villem
- Krjuse Kornelis Gerrit
- Tjulp Martinus Teodorus Marija
- Kejpers Vil'Ma
- Long Stiven Kennet
|
RU2178414C2 |
METHOD OF STEREOSELECTIVE SYNTHESIS OF HETEROBICYCLIC ALCOHOL ENANTIOMER, INTERMEDIATE COMPOUNDS AND METHODS OF THEIR SYNTHESIS |
1997 |
- Bejzer Nikolas
- Krjuse Kris Gerrit
- Shenk Klara Marija
- Shadid Belal
|
RU2185379C2 |
METHOD OF STEREOSELECTIVE SYNTHESIS OF HETEROBICYCLIC ALCOHOL ENANTIOMER, PURE ALCOHOL ENANTIOMER, METHOD OF SYNTHESIS OF PIPERAZINE DERIVATIVE |
1993 |
- Nikolas Bejzer
- Khris G.Krjuse
- Melle Van Der Lan
- Zhorzh Langran
- Gustaf J.M. Van Skharrenbjurg
- Marija K.Snoehk
|
RU2124506C1 |
ADDUCTS - ALDEHYDES AS INTERMEDIATE PRODUCTS FOR SYNTHESIS OF VITAMIN D DERIVATIVES |
1990 |
- Sebast'Janus J.Khalkes[Nl]
- Vil'Gel'Mus R.M.Overbek[Nl]
|
RU2036904C1 |
CYCLOALKYL NITRILE PYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS |
2014 |
- Chajlders Mettyu Llojd
- Dinsmor Kristofer
- Fuller Piter
- Gerin Devid
- Katts Dzhejson Devid
- Pu Tsinlin
- Skott Mark E.
- Tompson Kristofer F.
- Chzhan Khuntszyun
- Folkon Deniell
- Torres Luis
- Brubejker Dzhejson
- Tszen Khunbo
- Tsaj Tszyatsyan
- Du Syaosin
- Van Chungan
- Baj Yunfyn
- Kun Norman
- Lyu Yujmej
- Chzhen Chzhisyan
|
RU2655380C2 |
2-AMINOBENZOXAZOLE CARBOXAMIDES AS 5-HT3 MODULATORS |
2007 |
- Fehjrfaks Dehvid Dzh.
- Jan Chzhitsaj
|
RU2448105C2 |
[(BENZODIOXANE, BENZOFURAN OR BENZOPYRANE)-ALKYLAMINO]-ALKYL- -SUBSTITUTED GUANIDINES AS SELECTIVE VASOCONSTRICTORS, METHODS OF THEIR SYNTHESIS, INTERMEDIATES FOR THEIR, PHARMACEUTICAL COMPOSITION AND A METHOD OF ITS PREPARING |
1993 |
- Gi Rozalia Ozhen Van Lomman
- Marsel' Fran Leopol'D De Brjujen
- Val'Ter Zhakobjus Zhozef Zhanssen
|
RU2121999C1 |
PICOLINEAMIDE DERIVATIVES, METHOD OF PREPARING THEREOF, PYRIDINE-6-CARBONITRILE, HERBICIDAL COMPOSITION, METHODS OF CONTROLLING UNDESIRED VEGETATION |
1993 |
- Aksel' Kleemann
- Robert Dzhon Griffit Sirl
|
RU2130021C1 |
DERIVATIVES OF (AZETHIDINE-1-YLALKYL)-LACTAMES, PHARMACEUTICAL COMPOSITION BASED ON THEREOF AND METHOD OF TREATMENT OF HUMANS WHEN PATIENTS ARE TREATED BY PRODUCING ANTAGONISTIC EFFECT ON TACHYKININ ACTING IN HUMAN NK-, NK- AND NK-RECEPTORS OR IN THEIR COMBINATION |
1995 |
- Makenzi Aleksandr Roderik
- Marchington Alan Patrik
- Middlton Donal'D Stjuart
- Midouz Sandra Dora
|
RU2150468C1 |