FIELD: molecular biology, pharmacology. SUBSTANCE: composition is a liposomal vesicle containing a protein preparation. Liposome is one of phospholipids and protein is a hemopoietic factor, in part, cytokin, G-CSF, or GM-CSF. Invention describes also a method of preparing a composition at pH = 3.0-7.5 at ratio of lipid to protein = 10:1, not less. EFFECT: broadened pattern of liposomal forms of drugs. 23 cl, 19 dwg, 1 tbl, 6 ex
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Authors
Dates
1998-10-10—Published
1994-09-29—Filed