PROLONGED RELEASE OF ANTI-INFECTIOUS AGENTS Russian patent published in 2012 - IPC A61K9/127 

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to medicine, specifically pharmaceutics. What is created is a liposome preparative form of aminoglycoside with a lipid double layer and encapsulated aminoglycoside, in which a bulk amount of lipid makes less than or equal to an amount of aminoglycoside with the lipid double layer containing neutral phospholipid and sterol, and liposome has an average diameter 0.1 to 0.5 micron. Also, the present invention refers to a method of treating a patient with a pulmonary infection which involves administration of a therapeutically effective amount of the lipid anti-infectious preparative form in the patient, and to a method of treating a patient suffering mucoviscidosis which is based on administration of a therapeutically effective amount of the lipid anti-infectious preparative form according to the present invention in the patient.

EFFECT: use of the declared liposome anti-infectious agent provides a prolonged systemic therapeutic effect by prolonged release.

79 cl, 6 ex, 13 tbl, 9 dwg