2-AMINO-1,2,3,4-TETRAHYDRONAPHTALENE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, AND COMPOSITION HAVING CARDIOVASCULAR ACTIVITY Russian patent published in 1998 - IPC

Abstract RU 2120435 C1

FIELD: pharmaceutical industry. SUBSTANCE: present invention describes 2- amino-1,2,3,4-tetrahydronaphthalene derivatives of formula I: R1 and R2 wherein OY′ and Y′ are the same or different and are hydrogen or acyl of ethylcarbamic acid; R3 is hydrogen or alkyl; R4 and R5 are the same or different and are hydrogen, halogen, alkyl or alkoxy; m is 1-2 n is 3-7, or pharmaceutically acceptable salts thereof. Pharmaceutical composition comprising, as active ingredient, compound I has cardiovascular activity. Compounds I are dopaminoergic receptor agonists which are also active when administered orally. They have prolonged activity due to which fact they are useful for treating cardiovascular diseases. EFFECT: improved properties of the pharmaceutical composition. 2 cl, 11 ex, 2 tbl. v

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RU 2 120 435 C1

Authors

Franchesko Santangelo

Giorgio Bertolini

Chezare Kasagrande

Franchesko Marchini

Stefanija Montanari

Klaudio Semeraro

Dates

1998-10-20Published

1993-03-13Filed