1,2,3,4-TETRAHYDROQUINOXALINE DERIVATIVE, METHOD FOR ITS OBTAINING AND ITS APPLICATION Russian patent published in 2023 - IPC C07D241/44 C07D241/50 C07D471/04 C07D487/04 C07D491/04 C07D498/04 C07D513/04 A61K31/498 A61K31/4985 A61K31/499 A61K31/5383 A61K31/542 A61P3/00 A61P35/00 A61P37/00 

Abstract RU 2804127 C2

FIELD: chemistry.

SUBSTANCE: compound of Formula (IIb), its stereoisomer or a pharmaceutically acceptable salt.

also relates to a method for preparing a compound of Formula (IIb), a stereoisomer or a pharmaceutically acceptable salt thereof, also relates to the use of a compound of Formula (IIb), a stereoisomer or a pharmaceutically acceptable salt thereof for the manufacture of preparations for the treatment of one or more types of tumors, malignancies, metabolic diseases, autoimmune diseases or disorders associated with RORγt.

EFFECT: ensuring the development of a low molecular weight RORγt agonist having the structure of Formula (IIb).

12 cl, 1 tbl, 122 ex

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RU 2 804 127 C2

Authors

Zhao, Baowei

Xun, Guoliang

Zhao, Yuan

Feng, Tao

Yu, Hongping

Chen, Zhui

Xu, Yaochang

Dates

2023-09-26Published

2019-09-12Filed