2-PHENYLBENZO [B] FURANS AND THIOPHENES, AND METHOD OF PREPARATION THEREOF Russian patent published in 1998 - IPC

Abstract RU 2120443 C1

FIELD: medicine, more particularly 2-phenyl-benzo (b) furan and thiophene derivatives which are useful for treating extrogen-dependent diseases. SUBSTANCE: in order to produce benzo (b) thiophenes, orthothiomethyl styrene is cyclized by means of mixture of sulfuryl chloride and pyridine. In this case, as reaction proceeds, orthothiomethyl styrene is converted to corresponding sulfochloride which is converted by means of pyridine to chlorosulfide as methyl chloride is detached, and is then cyclized as HCl is separated into benzo (b) thiophene. EFFECT: improved properties of the title compounds. 4 cl, 4 dwg, 5 tbl

Similar patents RU2120443C1

Title Year Author Number
NOVEL COMPOUNDS OF 2-ARYLTHIAZOLE AS AGONISTS OF PPAR α AND PPAR γ 2003
  • Bindzheli Al'Fred
  • Greter Uve
  • Khil'Ert Khans
  • Irt Zhorzh
  • Mehrki Khans-Peter
  • Mejer Markus
  • Mor Peter
RU2296754C2
2-PHENYLIMIDAZO[1,2-A]PYRIMIDINES AS IMAGING AGENTS 2014
  • Gobbi Luka
  • Knust Khenner
  • Kerner Mattias
  • Muri Diter
RU2665580C2
DERIVATIVES OF AMIDINES, COMPOUNDS, PHARMACEUTICAL COMPOSITION 1999
  • Ovehn Serzh
  • Shabrie De Ljason'Er P'Er-Eht'Enn
  • Arnet Zheremia
  • Pon Dominik
  • Julibarri Zherar
RU2238939C2
DERIVATIVES OF 2,1,3-BENZOTHIADIAZOLE, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION AND MEDICINAL AGENT 1997
  • Dorsh Diter
  • Ossval'D Matias
  • Mederski Verner
  • Vil'M Klaudia
  • Shmitges Klaus
  • Kristadler Marija
  • Antsali Zokhajla
RU2175320C2
DERIVATIVES OF BETA-AMINO ACID NITRILES 2001
  • Tobias Gabriel'
  • Mikhaehl' Pekh
  • Roza-Marija Rodriges-Sarm'Ento
RU2245871C2
PYRROLIDINE DERIVATIVES AND A METHOD OF THEIR SYNTHESIS 1990
  • Motosuke Jamanaka[Jp]
  • Tomonori Khosiko[Jp]
  • Sindzi Suda[Jp]
  • Naoki Eneda[Jp]
  • Nobujuki Mori[Jp]
  • Mitsumasa Sino[Jp]
  • Khiroki Isikhara[Jp]
  • Mamoru Saito[Jp]
  • Tosijuki Matsuoka[Jp]
RU2024506C1
OXAZOLE DERIVATIVES SUBSTITUTED WITH CARBOXYLIC ACIDS AS PPAR-ALPHA AND PPAR-GAMMA ACTIVATORS IN DIABETES TREATMENT 2002
  • Binggeli Al'Fred
  • Beringer Markus
  • Greter Uve
  • Khil'Pert Khans
  • Mehrki Khans-Peter
  • Mejer Markus
  • Mor Peter
  • Riklen Fab'En
RU2278859C2
2,6-SUBSTUTED-4-MONOSUBSTITUTED AMINO-PYRIMIDINES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS 2005
  • Lim Sungtaek
  • Kharris Kejt Dzhon
  • Stefani Dehvid
  • Gardner Charl'Z Dzh.
  • Tsao Bin
  • Boffi Rehj
  • Gillespi Timoti A.
  • Agiar Zhuasi K.
  • Khant Khejzel Dzh.
  • Desho Ehl'Za A.
RU2417990C2
SUBSTITUTED METHYLPHENYL KETONES SUITABLE FOR USE AS PDE4 INHIBITORS 2007
  • Felding Jakob
  • Nil'Sen Simon Fel'Dbek
RU2493149C2
BENZOTHIOPHENE COMPOUNDS OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS 1996
  • Alan Dehvid Pal'Kovich
  • Kennet Dzheff Trehsher
RU2158737C2

RU 2 120 443 C1

Authors

Ehrvin Fon Angerer

Sebastian Ehrber

Martin Shnajder

Dates

1998-10-20Published

1992-05-25Filed