FIELD: organic chemistry, heterocyclic compounds, pharmacy. SUBSTANCE: invention relates to derivatives of substituted 4-phenylthiazoles of the formula (I) 
where values R1, A, R and Y are given in description, or their salts and also a method of their synthesis, and a pharmaceutical composition based on thereof. New compounds and a pharmaceutical composition are effective inhibitors of thromb aggregation, in part, they are antagonists of receptors GPIIb/IIIa. EFFECT: improved method of synthesis, enhanced antithrombotic activity. 14 cl, 1 dwg, 4 tbl, 45 ex
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