DERIVATIVES OF 2-BENZOYL-IMIDAZO [1,2-a] PIRIDINE, THEIR PRODUCTION AND THEIR APPLICATION IN THERAPY Russian patent published in 2012 - IPC C07D471/04 A61K31/437 A61P19/00 A61P35/00 A61P25/00

Abstract RU 2442785 C1

FIELD: chemistry.

SUBSTANCE: present invention refers to the field of chemistry of heterocyclic compounds, and in particular to the compound of formula where X denotes a phenyl group; R₁, R₃ and R₄ denote hydrogen atoms; R₂ denotes a non-saturated monocyclic heterocyclic group containing 5 or 6 atoms including from 1 to 2 heteroatoms chosen from N and O; the mentioned heterocyclic group can be replaced by the group -NRcRd; Rc and Rd denotes hydrogen; in the form of a hexone base or acid additive salt. The invention also refers to a drug and pharmaceutical composition based on the formula (I) compound, to application of the formula (I) compound for preparation of the drug. Besides, the invention describes the compound of phenyl[6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)imidazo[1,2-a]piridin-2-yl]methanone and its application in synthesis of the formula (I) compounds.

EFFECT: new compounds of imidazo[1,2-a]piridines that are applicable in treatment or prevention of diseases in which NOT receptors are active.

15 cl, 2 tbl, 6 ex

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RU 2 442 785 C1

Authors

Pehronel' Zhan-Fransua

Dates

2012-02-20—Published

2008-12-31—Filed