FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to pharmacology and describes new drug for treatment of patients with irritable colon syndrome. Invention proposes antagonists of 5-HT-receptors - a compound of the general formula (I): where R1 means lower alkyl or hydrogen; m = 2 or 3; n = 2 or 3. Analgetic effect of this agent exceeds that of the known compound. EFFECT: enhanced effectiveness of an agent proposed. 4 cl, 2 ex, 4 tbl, 1 dwg
Title |
Year |
Author |
Number |
METHOD FOR PREPARING IMIDAZOLYL COMPOUNDS |
2003 |
- Verbek Jan-Marten
- Van Der Mej Pauljus F.K.
|
RU2314296C2 |
DERIVATIVES OF [2R,3R(2′R,3′R),6R,7S,8S,9R,10R]-3-(2′,3′-DIHYDROXYPENT-2′-YL)- -2,6,8,10,12-PENTAMETHYL-4,13-DIOXOBICYCLO [8,2,1]-TRIDEC-12-ENE-5-ON, METHOD FOR THEIR PRODUCTION, PHARMACEUTICAL AGENT |
1992 |
- Dagmar Khel'T'E[De]
- Ulf Projshoff[De]
- Kristian Ehkkhout[Nl]
|
RU2107070C1 |
BENZAZEPIN, BENZOXAZEPIN OR BENZOTHIAZEPIN-N-ACETIC ACID, METHOD OF PREPARATION THEREOF, AND DRUG CONTAINED THEREIN |
1996 |
- Kharal'D Valdek
- Dagmar Khelt'E
- Jozef Messinger
- Jokhen Antel'
- Mikhel' Vurl
- Dirk Tormelen
|
RU2159768C2 |
ANTIHYPERGLYCAEMIC ACTIVITY OF PHARMACEUTICAL COMPOSITION |
1995 |
- Ehl'Bert Kaan
- Diter Tsigler
- Rajnkhard Brjukner
|
RU2145857C1 |
DIHYDROPYRIDOPHTHALAZINONE INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE |
2009 |
|
RU2514937C2 |
DERIVATIVES OF CONDENSED POLYCYCLIC HETEROCYCLIC COMPOUNDS AND METHOD OF THEIR SYNTHESIS |
1996 |
- Khirojuki Sugumi
- Dzun Niidzima
- Josikhiko Kotake
- Tosimi Okada
- Dzun-Iti Kamata
- Kentaro Josimatsu
- Takesi Nagasu
- Katsudzi Nakamura
- Tosimitsu Uenaka
- Atsumi Jamaguti
- Khirosi Josino
- Nozomu Kojanagi
- Kiosuke Kito
|
RU2167877C2 |
DIHYDRODIAZEPINES USEFUL AS INHIBITORS OF PROTEIN KINASE |
2007 |
- Sharr'E Zhan-Dam'En
- Kehj Dehvid
- Negtel Ronal'D
- Tvin Khiter
|
RU2475488C2 |
1,7-ANULAR DERIVATIVES OF 3-(PIPERAZINOALKYL)-INDOLE, METHOD OF THEIR SYNTHESIS (VARIANTS), PHARMACEUTICAL COMPOSITION CONTAINING THEREOF AND AN INTERMEDIATE COMPOUND FOR THEIR SYNTHESIS |
1992 |
- Daniehl' Zhasseran[Us]
- Dominik Pari[Us]
- Patris Demonsho[Us]
- Mishel' Kottin[Us]
- Fransua Flosh[Us]
- P'Er Djupass'E[Fr]
- Richard Vajt[Us]
|
RU2083580C1 |
METHOD OF PREPARING ENANTIOMERICALLY PURE IMIDAZOLYL COMPOUNDS, ENANTIOMERICALLY PURE ACID ADDITION SALT OF IMIDAZOLYL AND D-OR L-PYROGLUTAMIC ACID, AND HYDROCHLORIDE MONOHYDRATE OF ENANTIOMERICALLY PURE IMIDAZOLYL COMPOUNDS |
1996 |
- Pauljus Fransiskus Kornelis Van Der Mej
- Jan-Marten Verbek
|
RU2162085C2 |
DERIVATIVES OF UREA, METHOD OF THEIR SYNTHESIS (VARIANTS) AND MEDICINAL AGENT |
1998 |
- Zhasseran Daniel'
- Dehvid Samuehl'
- Antel' Jokhen
- Brjukner Rajnkhard
- Ehkkhout Kristian
- Bilenberg Gerkhard-Vil'Khel'M
|
RU2198883C2 |