3-{2-[4-(6-FLUOROBENZO[D]ISOXAZOLE-3-YL)-3,6-DIHYDRO-2H- -PYRIDINE-1-YL]-ETHYL}-2-METHYL-6,7,8,9-TETRAHYDROPYRIDO- -[1,2-A]-PYRIMIDINE-4-ONE AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS, METHOD OF ITS SYNTHESIS, METHOD OF PRODUCING SALT OF 1-[2-(2-METHYL-4-OXO-6,7,8,9-TETRAHYDRO-4H-PYRIDO-[1,2-A]- -PYRIMIDINE-3-YL)ETHYL]-4-(6-FLUOROBENZO[D]ISOXAZOLE-3-YL)- -PYRIDINIUM, PHARMACEUTICAL COMPOSITION Russian patent published in 1999 - IPC

Abstract RU 2126005 C1

FIELD: organic chemistry, heterocyclic compounds, pharmacy. SUBSTANCE: invention relates to a compound of the formula (I) that shows neuroleptic property. Compound (I) is synthesized by partial reduction of pyridinium salt of compound of the formula (IV) where W - an organic or an inorganic ion with metal boron hydride in protonic solvent. Synthesized compound is used for treatment of patients with schizophrenia and other psychosis. EFFECT: improved method of synthesis and producing, enhanced efficiency. 9 cl, 5 ex

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RU 2 126 005 C1

Authors

Khose Marija Kal'Dero Khes

Klotet Khoan Uget

Fransisko Markil'Jas Olondris

Pere Dalmases Barkhoan

Anna Bosh Rovira

Khoan Roka Asin

Khuan Karlos Del' Kastil'O N'Eto

Dates

1999-02-10Published

1995-02-02Filed