EXPRESSION METHOD Russian patent published in 1999 - IPC

FIELD: biotechnology and genetic engineering. SUBSTANCE: host mammalian cells are transfected with vector adapted for expression of aminopeptidase antigen H 110D or its fragment. Prior to transfection, host cells are freed of endogenous enzymes possessing the same function and the same integration with cell membrane or its absence as aminopeptidase antigen H 110D or its fragment. Host cell is COS-1 or CH-0 cell. Aminopeptidase antigen H 110D or its fragment is expressed integrated with host cell membrane and/or soluble cytoplasmic enzyme. EFFECT: enabled expression of antigens integrated with membrane of helminth aminopeptidases. 5 cl, 2 dwg, 4 tbl, 2 ex