FIELD: genetic engineering, molecular biology. SUBSTANCE: protein chimeric receptor has intracellular and extracellular compartments. Invention describes intracellular compartment with human and porcine amino acid sequence Syk given in description. Intracellular compartment is able to transfer signal to receptor of disruption of signal-associated cell-target or infectious agent of target. Extracellular compartment has region CD 4 binding with HIV envelope. Invention presents DNA encoding protein chimeric receptor. Invention ensures to switch over the potential that recognizes targets by cells of immune system and direct its to antigen that is recognized by extrecellular compartment of antibody. EFFECT: protein and DNA indicated above, valuable biological properties. 3 cl, 19 dwg
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