DNA PCG-2,6 FRAGMENT ENCODING SYNTHESIS OF SECRETED BETA-GALACTOSIDASE OF PENICILLIUM CANESCENS AND THE STRAIN OF FUNGUS PENICILLIUM CANESCENS - PRODUCER OF SECRETED BETA-GALACTOSIDASE Russian patent published in 1999 - IPC

FIELD: microbiological industry, genetic engineering, biotechnology, enzymology. SUBSTANCE: PCG-2,6- -fragment of DNA (size is 6.3 thousand nucleotide pairs) carries the complete structural part of gene that encodes beta-galactosidase and functionally complete regulatory site of this gene. On the basis of this fragment the strain Penicillium canescens VKPM F-725 as a producer of beta-galactosidase is constructed. The yield of this enzyme in cultural fluid is 605-620 U/ml for 96-108 h fermentation. EFFECT: increased yield of beta-galactosidase by the strain. 3 cl, 1 dwg, 1 tbl, 4 ex