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2 126 253

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(51)

IPC

(21) (22)

Application

96111178/14, 1996-06-06

(22)

Actual filing date

1996-06-06

(45)

Published

1999-02-20

(72)

Inventor

Surkov K.G.Tsyrlina E.V.Bershtejn L.M.

(73)

Holder

Surkov Kirill Gennad'EvichTsyrlina Evgenija VladimirovnaBershtejn Lev Mikhajlovich

AGENT INDUCING ESTROGEN AND PROGESTINE RECEPTORS Russian patent published in 1999 - IPC

Abstract RU 2126253 C1

FIELD: medicine and veterinary. SUBSTANCE: invention provides drugs causing increase in level of progesterone and estrogen receptors in target cells in the course of treatment of uterine and mammary gland tumors in mammalians, overcoming and preventing development of hormonal resistance of these tumors. Those drugs are esters and salts of 10-methylenecarboxylate-9- acridone. Drugs exhibit lower adverse effects than known inductors while retaining comparable or larger capacity for such induction. EFFECT: enhanced therapeutic efficiency. 2 tbl, 2 ex

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RU 2 126 253 C1

Authors

Surkov K.G.

Tsyrlina E.V.

Bershtejn L.M.

Dates

1999-02-20—Published

1996-06-06—Filed