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2 317 555

(13)

(51)

IPC

G01N33/74(2006-01-01)

(21) (22)

Application

2006100526/15, 2006-01-10

(24)

Start date

2006-01-10

(22)

Actual filing date

2006-01-10

(45)

Published

2008-02-20

(72)

Inventor

Bershtejn Lev MikhajlovichKovalevskij Anatolij Jur'EvichMaksimov Sergej JanovichTsyrlina Evgenija Vladimirovna

(73)

Holder

Gun Nii Onkologii Im. Prof. N.N. Petrova Roszdrava

METHOD FOR ESTIMATING TUMOR HORMONE DEPENDENCE OF LOW-DIFFERENTIATED ENDOMETRIUM CARCINOMA AND ITS SENSITIVITY TO AROMATASE INHIBITORS Russian patent published in 2008 - IPC G01N33/74

Abstract RU 2317555 C2

FIELD: medicine.

SUBSTANCE: method involves determining aromatase activity and progesterone receptor content in tumor tissue. Progesterone receptor content being greater than 10 fM/mg of protein per 1 hour and aromatase activity being greater than fM/mg of protein, the neoplasm is considered to be hormone-sensitive, capable of responding to hormone therapy with aromatase inhibitors.

EFFECT: high accuracy in detecting hormone dependence cases.

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RU 2 317 555 C2

Authors

Bershtejn Lev Mikhajlovich

Kovalevskij Anatolij Jur'Evich

Maksimov Sergej Janovich

Tsyrlina Evgenija Vladimirovna

Dates

2008-02-20—Published

2006-01-10—Filed