APPLICATION OF 9-OCOACRIDINE-10-ACETIC ACID AND/OR ITS SALT COMBINED WITH ANTIESTROGEN AND/OR PROGESTIN FOR TREATMENT OF STROGEN-DEPENDENT TUMOURS, METHOD OF TREATMENT AND SETS Russian patent published in 2009 - IPC A61K31/7008 A61K31/138 A61K31/57 A61P35/00

Abstract RU 2346691 C2

FIELD: medicine; oncology and gynaecology.

SUBSTANCE: 9-oxoacridine-10-acetic acid (A) and/or its pharmaceutically acceptable salt are introduced in combinations with antiestrogen and/or progestin in amount effective to potentiate action of the specified antiestrogen and/or progestin. Thus (A) and/or its salt and/or ester combined with antiestrogen and/or progestin can be used as a preparation or as sets. Application of A and/or its salts and/or esters provide inhibition of NF-kappaB protein.

EFFECT: intensified sensitivity of uterine body or breast cancer cells to antiproliferative action of antiestrogen and progestin.

17 cl, 1 dwg, 5 tbl, 12 ex

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RU 2 346 691 C2

Authors

Surkov Kirill Gennadievich

Dates

2009-02-20—Published

2007-03-29—Filed