FIELD: medicine.
SUBSTANCE: invention refers to medicine, namely to oncology, and can be used for prediction of the pathological process direction in uterine body cancer. That is ensured by measuring the oncoprotein E6 and sex steroids – oestradiol, estrone, testosterone and progesterone in endometrial tumor tissue by ELISA. That is followed by calculating the ratio of sex steroids according to the original design formula. If values of oncoprotein E6 equal to 420±32 ng/g mq, and K, equal to 24.54±2.4, developing recurrences of the disease is predicted for up to 6 months after surgical management. If values of oncoprotein E6 equal to 28±2.1 ng/g mq, and K, equal to 8.15±1.2, recurrences are predicted in term of more than 6 months to 1 year after surgical treatment. If the oncoprotein E6 and K have negative values of 3.69±0.25, recurrence-free period more than 1 year after surgical management is predicted.
EFFECT: method enables predicting the pathological process in uterine body cancer following surgical treatment ensured by a personalized approach to therapeutic measures not envisaged by the treatment standards.
1 cl, 1 tbl, 3 ex
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Authors
Dates
2020-01-28—Published
2019-01-24—Filed