PHARMACEUTICAL COMPOSITIONS WITH NERVE GROWTH FACTORS Russian patent published in 1999 - IPC

Abstract RU 2126265 C1

FIELD: neurology. SUBSTANCE: invention provides stable aqueous pharmaceutical compositions with human nerve growth factor, containing aqueous isotonic buffered solutions with pH values from about 4.5 to about 6.0 and optionally containing carrier such as human serum albumin. Also provided are aqueous compositions with human nerve growth factor appropriate for lyophilization and subsequent reduction, wherein nerve growth factor is mixed with sugars, optionally with human serum albumin, and with buffer. Compositions are effective in treatment of Alzheimer disease and other nervous disturbances. EFFECT: increased stability with regard to biological activity. 14 cl, 5 tbl, 9 ex

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RU 2 126 265 C1

Authors

Viktorija M.Knepp

Debora M.Lidgejt

Richard Maskivich

Leo Gu

Dates

1999-02-20Published

1994-08-16Filed