IMIDAZOAZEPINE DERIVATIVE, PHARMACEUTICAL COMPOSITION, METHOD OF ITS PREPARING, METHOD OF SYNTHESIS OF IMIDAZOAZEPINE DERIVATIVE Russian patent published in 1999 - IPC

FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to the novel imidazoazepines of the formula (I), their pharmaceutically acceptable additive salts and stereochemically isomeric forms where each of the dotted lines means independently the optional bond; -A-B- means radical of the formula: -X-C=CH (a-1), -CH=CH-X- (a-2) or -CH=CH-CH=CH- (a-3) where X means O, S or NR¹ where R¹ means H or C_1-6-alkyl; means the radical of the formula: = O (b-1), -OH (b-2) or =N-OH (b-3); and L means hydrogen atom, C_1-4-alkyloxycarbonyl, C_1-6-alkyl or C_1-6-alkyl substituted with C_1-4-alkyloxycarbonyl, aryl, aryloxy-group or the radical of the formula (C) where D-Z means -S-CH=CH- and aryl means phenyl or phenyl substituted with halogen atom, hydroxy- or C_1-4-alkyloxy-group. Invention describes compositions containing the compounds, methods of their synthesis and use for treatment of patients with allergic sicknesses. EFFECT: improved method of synthesis and preparing the anti-allergic compounds. 14 cl, 19 ex