FIELD: biotechnology, microbiology, steroids. SUBSTANCE: invention relates to a microbiological method of androst-4-ene-3,17-dione producing. The strain Mycobacterium smegmatis able to transform plant and animal sterols (for example, sitosterol, cholesterol) to androst-4-ene-3,71-dione. The strain Mycobacterium smegmatis is deposited in VKPM at number Ac-1552. Strain is resistant to streptomycin that ensures to use its without risk to infect medium by foreign microflora. Strain VKPM Ac-1552 provides producing the end product at concentration 7-9 g/l. EFFECT: increased yield of the end product. 1 ex
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