FIELD: biotechnology, microbiology, steroids.
SUBSTANCE: strain Mycobacterium neoaurum deposited in VKPM at number VKPI, Ac-1634, is able to transform animal and vegetable sterols (cholesterol and phytosterols) to androst-4-ene-3,17-dione. The strain provides preparing the end product without impurity of steroids with underoxidized by-side chain in the concentration up to 7-12 g/l in loading the parent sterol from 10 to 30 g/l, respectively. The strain is able to transform phytosterols of any composition effectively.
EFFECT: improved and valuable properties of strain.
2 cl, 1 tbl, 4 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR PRODUCTION OF ANDROSTA-1,4-DIENE-3,17-DIONE FROM PLANT AND ANIMAL DERIVED STEROLS | 2005 |
|
RU2297455C2 |
| STRAIN OF BACTERIUM MYCOBACTERIUM SMEGMATIS USED FOR OXIDATION OF PLANT AND ANIMAL STEROLS TO ANDROST-4-ENE-3,17-DIONE | 1997 |
|
RU2126837C1 |
| METHOD FOR PREPARING ANDROST-4-EN-3,17-DIONE OR THEIR DERIVATIVES FROM STEROL OF VEGETABLE AND ANIMAL ORIGIN | 1998 |
|
RU2205224C2 |
| STRAIN PIMELOBACTER SIMPLEX ELICITING STEROID-1,2-DEHYDROGENASE ACTIVITY | 2001 |
|
RU2215038C2 |
| STRAIN Rhodococcus erythropolis "ВКПМ" Ac-1740 FOR 9 ALPHA-HYDROXYSTEROIDS | 2007 |
|
RU2351645C1 |
| METHOD FOR PREPARING METANDROSTENOLONE | 2002 |
|
RU2236464C2 |
| METHOD OF SYNTHESIS OF γ-LACTONE 3 OF (7α-ACETYLTHIO-17β-HYDROXY-3-OXOANDROST-4-ENE-17α-YL)-PROPIONIC ACID | 1999 |
|
RU2163606C1 |
| METHOD OF PREPARING PREGNANES | 1999 |
|
RU2156255C1 |
| METHOD OF PREPARING CORTICOSTEROIDS | 1999 |
|
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| RECOMBINANT MYCOBACTERIAL PRODUCER STRAINS AND THEIR USE TO PRODUCE 22-FUNCTIONALISED STEROIDS | 2019 |
|
RU2767610C2 |
