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2 351 645

(13)

(51)

IPC

C12N1/20(2006-01-01)

C12P33/06(2006-01-01)

C12R1/02(2006-01-01)

(21) (22)

Application

2007127776/13, 2007-07-20

(24)

Start date

2007-07-20

(22)

Actual filing date

2007-07-20

(45)

Published

2009-04-10

(72)

Inventor

Vojshvillo Natalija Evgen'EvnaRodina Natal'Ja ViktorovnaAndrjushina Valentina AleksandrovnaStytsenko Tat'Jana SemenovnaSkrjabin Konstantin Georgievich

(73)

Holder

Vojshvillo Natalija Evgen'EvnaRodina Natal'Ja ViktorovnaAndrjushina Valentina AleksandrovnaStytsenko Tat'Jana SemenovnaSkrjabin Konstantin GeorgievichTsentr Ran

STRAIN Rhodococcus erythropolis "ВКПМ" Ac-1740 FOR 9 ALPHA-HYDROXYSTEROIDS Russian patent published in 2009 - IPC C12N1/20 C12P33/06 C12R1/02

Abstract RU 2351645 C1

FIELD: chemistry, biochemistry.

SUBSTANCE: invention refers to biotechnology and to be used in pharmaceutical industry. Strain Rhodococcus erythropolis "ВКПМ" Ac-1740 resulted from actinobacteria selection, is able to introduce 9α-hydroxygroup into steroid line of hydrosterone, pregnane, estrane and does not produce 1,2-dehydrogenase. Utilisation of the invention allows for high 9α-hydroxylase activity both on common mediums, and high dimethyl formamide content mediums.

EFFECT: ensured high 9α- hydroxylase activity both on common mediums, and high dimethyl formamide content mediums.

2 tbl, 9 ex

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RU 2 351 645 C1

Authors

Vojshvillo Natalija Evgen'Evna

Rodina Natal'Ja Viktorovna

Andrjushina Valentina Aleksandrovna

Stytsenko Tat'Jana Semenovna

Skrjabin Konstantin Georgievich

Dates

2009-04-10—Published

2007-07-20—Filed