METHOD OF SYNTHESIS OF 4-METHOXY-10-(1-HYDROXYETHYL)-11-OXO- -1-AZATRICYCLO-[7.2.0.0]-UNDECA-2-ENE CARBOXYLIC ACID OR ITS SALTS, 4-TERTIARY-BUTYLBENZYL-(4S, 8S, 9R, 10S, 12R)-4-METHOXY-10- -(1-HYDROXYETHYL)-11-OXO-1-AZATRICYCLO-[7.2.0.0]-UNDECA-2-ENE-2 CARBOXYLATE Russian patent published in 1999 - IPC

Abstract RU 2127735 C1

FIELD: organic chemistry. SUBSTANCE: invention relates to a method of synthesis of an antibacterial compound of the formula (I) or its salt that involves hydrogenolysis of a new compound of the formula (II) and if necessary an isolation of synthesized carboxylic acid as its salt. Invention proposes also a compound of the formula (II) used as an intermediate substance for synthesis of a compound of the formula (I). The use of compound of the formula (II) simplifies purification stage if it is necessary before the end synthesis stage carrying out. EFFECT: improved and simplified method. 9 cl, 6 ex

Similar patents RU2127735C1

Title Year Author Number
ESTERS OF 10-(1-HYDROXYETHYL)- 11-OXO-1 -AZATRICYCLO- [7,2,0,0]-UNDEC- 2-ENE-2- CARBOXYLIC ACID AND A METHOD OF THEIR SYNTHESIS 1992
  • Al'Chide Perboni[It]
  • Tino Rossi[It]
  • Dzhovanni Gavirachi[It]
  • Dzhordzho Tartsija[It]
  • Antonella Ursini[It]
RU2043354C1
HETEROCYCLIC COMPOUND 1992
  • Bruno Tamburini[It]
  • Al'Chide Pervoni[It]
  • Tino Rossi[It]
  • Daniehle Donati[It]
  • Daniehle Andreotti[It]
  • Dzhovanni Gaviragi[It]
  • Roberto Karlesso[It]
  • Klaudio Bismara[It]
RU2054006C1
INDOLE DERIVATIVES 1994
  • Kugola Al'Fredo
  • Di Fabio Romano
  • Pentassul'Ja Dzhordzhio
RU2144535C1
DERIVATIVES OF SORDARINE AND PHARMACEUTICAL COMPOSITION WITH ANTIFUNGAL ACTIVITY BASED ON THEREOF 1995
  • Gomes Khose Ramon Ruis
  • Kal'Deron Khose Marija Buehno
  • Garsia-Ochoa Dorado Sil'Vestre
  • Frajle Gabal'Don Marija Teresa
  • Pichel' Khul'Ja Kastro
  • Fiandor Roman Khose
  • Gargal'O Viola Domingo
  • Kuehvas Surita Khuan Karlos
  • Lavandera Dias Khose Luis
  • Khuss Sof'E
RU2152398C1
5-HETEROCYCLO-1,5-BENZODIAZEPINES AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS 1995
  • Akvino Kristofer Dzhozef
  • Sagg Ehlizabet Ehllen
  • Sevchik Dzherzi Risard
RU2152939C1
5-AMINO-2-(1-HYDROXYETHYL)TETRAHYDROPYRAN DERIVATIVES 2009
  • Kristian Khubshverlen
  • Georg Rjuehdi
  • Zhan-Filipp Sjurive
  • Kornelia Tsumbrunn-Aklin
RU2525541C2
BORONIC ACID DERIVATIVES 2018
  • Klein Markus
  • Schadt Oliver
  • Esdar Christina
RU2793315C2
REGULATORS-DERIVATIVES OF STEROIDS, METHODS OF THEIR OBTAINING AND THEIR USE 2019
  • Su Yidong
  • Deng Haining
  • Chen Xiaopo
  • Bao Rudi
  • Zhang Fujun
RU2797408C2
2-AMINO-4-PHENYL-4-OXOBUTYRIC DERIVATIVES ACID AND PHARMACEUTICAL COMPOSITION 1994
  • Mario Virazi
  • Antonio Dzhiordani
  • Karmela Spechiale
  • Massimo Chini
  • Al'Berto B'Janketti
RU2139850C1
DERIVATIVES OF CYCLOHEXANE OR TETRAHYDROPYRANE OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS, OR HYDRATES, OR SOLVATES OF THESE COMPOUNDS, OR THEIR SALTS, INTERMEDIATE COMPOUNDS FOR THEIR SYNTHESIS AND FUNGICIDE AGENT 1992
  • Jukhko Aoki[Jp]
  • Khiromichi Kotaki[Jp]
  • Katsunao Masubuchi[Jp]
  • Toru Okuda[Jp]
  • Nobuo Shimma[Jp]
  • Takuo Tsakuda[Jp]
  • Isao Umeda[Jp]
RU2084439C1

RU 2 127 735 C1

Authors

Tagen Garfild Sesil

Dates

1999-03-20Published

1994-03-17Filed