FIELD: chemistry.
SUBSTANCE: invention relates to individual compounds comprising 4-hydroxy-1,2,3,4-tetrahydronaphthalene-1-yl-urea, and pharmaceutically acceptable salts thereof. Compounds of invention have properties of inhibitor of p38 MAP kinase. Invention also relates to pharmaceutical composition, to method for inhibiting p38 MAP kinase and to use of compounds in manufacture of medicament.
EFFECT: Technical result provided new compounds having properties of inhibitor of p38 MAP kinase, which are useful as anti-inflammatory agents in treatment of diseases of respiratory tract.
9 cl, 3 tbl, 34 ex
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Authors
Dates
2016-06-10—Published
2011-12-09—Filed