DERIVATIVES OF 4-HYDROXY-1,2,3,4-TETRAHYDRONAPHTHALENE-1-YL-UREA AND THEIR USE IN TREATMENT, INTER ALIA, DISEASES OF RESPIRATORY TRACT Russian patent published in 2016 - IPC C07D401/12 C07D471/04 A61K31/4196 A61K31/4439 A61K31/5375 A61P11/06 

Abstract RU 2586333 C1

FIELD: chemistry.

SUBSTANCE: invention relates to individual compounds comprising 4-hydroxy-1,2,3,4-tetrahydronaphthalene-1-yl-urea, and pharmaceutically acceptable salts thereof. Compounds of invention have properties of inhibitor of p38 MAP kinase. Invention also relates to pharmaceutical composition, to method for inhibiting p38 MAP kinase and to use of compounds in manufacture of medicament.

EFFECT: Technical result provided new compounds having properties of inhibitor of p38 MAP kinase, which are useful as anti-inflammatory agents in treatment of diseases of respiratory tract.

9 cl, 3 tbl, 34 ex

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RU 2 586 333 C1

Authors

Finch Harry

Van Niel Monique Bodil

Woo Chi-Kit

Dates

2016-06-10Published

2011-12-09Filed