FIELD: synthesis of biologically-active compounds. SUBSTANCE: invention provides new indole derivatives of general formula I: 
(I), wherein m=2, R is chlorine in positions 4 and 6 of indole nucleus, R1 is optionally substituted phenyl, A is chain including units 
, and their physiologically acceptable salts or metabolically labile esters, which are antagonists of exciting amino acids. Preparation procedure and medical applications are also provided. EFFECT: enlarged choice of biologically-active substances. 10 cl, 37 ex
| Title | Year | Author | Number |
|---|---|---|---|
| 5-HETEROCYCLO-1,5-BENZODIAZEPINES AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS | 1995 |
|
RU2152939C1 |
| DERIVATIVES OF 1,5-BENZODIAZEPINE, METHOD OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITION CONTAINING ON SAID | 1994 |
|
RU2135486C1 |
| METHOD OF SYNTHESIS OF 4-METHOXY-10-(1-HYDROXYETHYL)-11-OXO- -1-AZATRICYCLO-[7.2.0.0]-UNDECA-2-ENE CARBOXYLIC ACID OR ITS SALTS, 4-TERTIARY-BUTYLBENZYL-(4S, 8S, 9R, 10S, 12R)-4-METHOXY-10- -(1-HYDROXYETHYL)-11-OXO-1-AZATRICYCLO-[7.2.0.0]-UNDECA-2-ENE-2 CARBOXYLATE | 1994 |
|
RU2127735C1 |
| HETEROCYCLIC COMPOUND | 1992 |
|
RU2054006C1 |
| DERIVATIVES OF SORDARINE AND PHARMACEUTICAL COMPOSITION WITH ANTIFUNGAL ACTIVITY BASED ON THEREOF | 1995 |
|
RU2152398C1 |
| HETEROCYCLIC NITROGEN PYRROLE DERIVATIVES, PRODUCING THEM AND PHARMACEUTICAL APPLICATION | 2008 |
|
RU2473543C2 |
| DERIVATIVES OF BICYCLED AMIDES, PHARMACEUTICAL COMPOSITION AND METHOD OF TREATMENT OF PATIENTS WITH PATHOLOGICAL AND INFLAMMATORY STATES | 1994 |
|
RU2143422C1 |
| INDOLE DERIVATIVES, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION | 1993 |
|
RU2129544C1 |
| ANDROSTEN(ANE) (ONE) DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SOLVATE THEREOF, METHODS OF PREPARATION THEREOF, AND METHOD OF MEDICAL TREATMENT | 1994 |
|
RU2144037C1 |
| 2-(2-OXOINDOLIN-3-YLIDENE)METHYL-5-(2-HYDROXY-3-MORPHOLIN-4-YLPROPYL)-6,7-DIHYDRO-1-H-PYRROLE[3,2-C]PYRIDIN-4(5H)-ONE COMPOUNDS AND USE THEREOF AS PROTEIN KINASE INHIBITORS | 2008 |
|
RU2472792C2 |
