FIELD: molecular biology, immunology, pharmacy. SUBSTANCE: invention relates to a monoclonal antibody NMO1 that shows a specific immunoreactivity with respect to protein HIV-1 gp120 or gp160 and shows capability to neutralize in vitro infection of cells H9 by living strains of HIV-1. NMO1 antibodies are isolated by hybridoma cellular line ATCC N HB 10726. Invention proposes also pharmaceutical compositions that will use for treatment of patients with HIV-1 infection by passive immunization. EFFECT: enhanced effectiveness of antibody and cellular line isolated. 5 cl, 18 dwg, 5 tbl, 9 ex
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Authors
Dates
1999-03-27—Published
1992-08-24—Filed